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The working mode of the sterilization grade nitrile/latex glove production line

Sterilization grade gloves can be divided into two types:

1. After the nitrile/latex gloves are stripped from the glove production line, they are counted by the machine, bagged manually, and then sent to the ethylene oxide sterilization equipment for sterilization after packing. Such gloves can generally be used as ordinary inspection gloves.

2. After the nitrile/latex gloves are completely peeled from the hand mold, they are washed, spin-dried, and dried to wash off the impurities on the surface of the nitrile/latex gloves, and then the employees go to the aseptic workshop for bagging, Packing and boxing, and finally sent to ethylene oxide sterilization equipment for sterilization.


Ethylene oxide sterilization is the first choice for glove sterilization. The following is some information about ethylene oxide sterilization:


1. Sterilization principle of ethylene oxide sterilizer

The killing process is called “alkylation”

The effect of ethylene oxide on molecules in cells is irreversible

By destroying DNA, protein denaturation, protein and DNA hinges, purine and pyrimidine hinges are formed, so that the bacterial protein after the reaction loses activity, so as to achieve the effect of sterilization.


2. The characteristics and sterilization mechanism of EO ethylene oxide

Characteristics of EO ethylene oxide:

Molecular formula: C2H4O

Boiling point: 10.8℃

Hazard: Ethylene oxide is a flammable gas, which can be mixed with air to form an explosive mixture. It will burn and explode when exposed to sparks and high temperatures; it is also a toxic gas.

3. The main factors affecting the sterilization of ethylene oxide

Ethylene oxide concentration: usually 400 to 800mg/L

Humidity: usually refers to the relative humidity (usually not less than 30% RH); the reaction process of ethylene oxide and key cell molecules (alkylation process) requires water; it exists in a gaseous state during the sterilization process.

Temperature: The sterilization rate will increase with the increase of temperature; every time the temperature increases by 10℃, the killing rate of spores usually doubles.

Time: The sterilization rate will increase with the extension of the exposure time (ie EO residence time).

4. Introduction to the daily sterilization process

Pretreatment-Transfer-Initial Pumping-Leak Test-Moisture Injection / Holding Pressure-Gas Injection-EO Residency-Post Pumping-Scrubbing-Release-Analysis

Sterilization grade nitrile latex glove production equipment

Post time: Jun-24-2021